Noun
A
genetic disorder
caused
by
the
presence
of
all
or
part
of
a
third
copy
of
chromosome
21
(
a
chromosomal
excess
),
whereby
the
patients
typically
have
a
delay
in
cognitive
ability
and
physical
growth
,
as
well
as
a
small
head
and
tilted
eyelids
.